Exploring the therapeutic efficacy of angiocrine growth factors to enhance craniofacial cartilage growth and morphogenesis.
Exploring the therapeutic efficacy of angiocrine growth factors to enhance craniofacial cartilage growth and morphogenesis.
What are the biological programs that fail in craniofacial disorders?
What are the biological programs that fail in craniofacial disorders?
That's what Quenten Schwartz and his team are seeking to find out.
Dr. Quenten Schwarz is a developmental neuroscientist heading the Neurovascular Research Laboratory at the University of South Australia.
Project
Project
Associate Professor Schwartz and his team are researching the growth of the craniofacial skeleton, with particular interest in identifying what biological factors are failing when craniofacial deformities occur. The project focuses on two related objectives that explore what can be used to prevent or repair craniofacial defects.
Objective One
Investigating the potential role of angiocrine factors (molecules that can stimulate organ-specific repair activities) as therapeutics for jaw growth disorders.
Expected outcome
To provide proof-of-principle that angiocrine factors can enhance lower jaw growth and repair deformities.
Objective Two
Investigate the ability of dietary supplementation to reduce the severity of mandibular hypoplasia (undersized lower jaw) in foetal development.
Expected Outcome
To provide proof-of-principle that mothers dietary intake can directly interact with genetic modifications to alter the course of craniofacial development.
Research projects funded by Craniofacial Australia
Research projects funded by Craniofacial Australia
